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In addition, an optimized subset of the biomarkers identified autistic participants in the CAMP study with 72% sensitivity and 90% specificity

Subsequently, the cells were treated with BPTES (3 M, a glutaminase inhibitor that blocks the glutamine oxidation pathway), etomoxir (4 M, a CPT1A inhibitor, which is crucial for the transport of long-chain FAs from cytosol into mitochondria for oxidation), or UK5099 (2 M, an inhibitor of the glucose oxidation pathway that blocks the mitochondrial pyruvate carrier) successively, and oxygen consumption rate (OCR) was measured prior to and after the addition of each inhibitor